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Genome-wide analysis of Fcγ receptor ligation on dendritic cells from wild-type, FcγRIIb KO or FcR γ chain KO mice

ABSTRACT: Analysis of changes in gene expression after incubation of dendritic cells with immune complexes or medium. Since the dendritic cells are derived from three different mouse strains, either wild type, Fcγ receptor IIb KO (expresses only activating Fcγ receptors) or Fc receptor γ chain KO (expresses only inhibitory Fcγ receptor), the analysis gives important insight into the roles of the activating versus inhibiting Fcγ receptors on dendritic cells.

ORGANISM(S): Mus musculus

PROVIDER: GSE33718 | GEO | 2012/05/03

SECONDARY ACCESSION(S): PRJNA148463

REPOSITORIES: GEO

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