Transcriptomics

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Cockayne syndrome (CSB) fibroblasts


ABSTRACT: Cockayne syndrome (CS) is an inherited neurodevelopmental disorder with progeroid features. Although the genes responsible for CS have been implicated in a variety of DNA repair- and transcription-related pathways, the nature of the molecular defect in CS remains mysterious. We sought to define this defect by expression analysis of cells lacking functional CSB, a SWI/SNF-like ATPase that is responsible for most CS cases. Keywords: primary disease rescue

ORGANISM(S): Homo sapiens

PROVIDER: GSE3407 | GEO | 2006/07/14

SECONDARY ACCESSION(S): PRJNA93425

REPOSITORIES: GEO

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