Transcriptomics

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Polyphenols protection against fructose overload


ABSTRACT: To decipher the beneficial effects of Polyphenols on health, healthy volunteers were randomized into two groups and were submitted to either a red grape polyphenol rich extract supplemented diet (PP) or a placebo diet (PCB) during 8 weeks. Then they were submitted to a fructose load (3g/kg Fat Free Mass/day) during 7 days. Muscle biopsies were taken before the protocol, 8 weeks after PP or PCB diet and after the 7 days fructose load. We have employed whole genome microarray expression profiling as a discovery platform to identify genes regulated by fructose and to identify the mechanism of action of Polyphenols.

ORGANISM(S): Homo sapiens

PROVIDER: GSE35764 | GEO | 2013/02/04

SECONDARY ACCESSION(S): PRJNA152107

REPOSITORIES: GEO

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