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Expression data SK-N-SH cells treated with risperidone

ABSTRACT: We performed a pharmacotranscriptomic analysis of a human neuroblastoma cell line (SK-N-SH) exposed to risperidone to identify molecular mechanisms involved in the cellular response to risperidone and thus identify candidate genes for pharmacogenetic studies. This study is a part of a convergent functional genomic approach that plans to integrate the data presented here with: data from gene expression analysis of experimental animal brain under treatment with risperidone; and data from gene expression analysis of peripheral blood from first psychotic patients treated with risperidone.

ORGANISM(S): Homo sapiens

PROVIDER: GSE36678 | GEO | 2012/03/22

SECONDARY ACCESSION(S): PRJNA153585

REPOSITORIES: GEO

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Expression data SK-N-SH cells treated with risperidone

Project description:We performed a pharmacotranscriptomic analysis of a human neuroblastoma cell line (SK-N-SH) exposed to risperidone to identify molecular mechanisms involved in the cellular response to risperidone and thus identify candidate genes for pharmacogenetic studies. This study is a part of a convergent functional genomic approach that plans to integrate the data presented here with: data from gene expression analysis of experimental animal brain under treatment with risperidone; and data from gene expression analysis of peripheral blood from first psychotic patients treated with risperidone. Gene expression was assessed by microarray (Human Genome U219 Array) in cells treated with risperidone 10 ÂµM at 6, 24 and 48 h

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SK-N-SH Hi-C

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