Transcriptomics

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MiR-155 promotes Th17 development by targeting Jarid2


ABSTRACT: Genome-wide analysis was performed on microRNA 155+/+ and -/- Th17 cells to determine the differentially expressed transcripts that are regulated by miR-155. We found that Jarid2 was differentially expressed in absence of miR-155 and highlight the mechanism for the silencing of IL-22 by Jarid2 and PRC2 in miR-155-/- Th17 cells.

ORGANISM(S): Mus musculus

PROVIDER: GSE37228 | GEO | 2014/10/12

SECONDARY ACCESSION(S): PRJNA158955

REPOSITORIES: GEO

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