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Chemical perturbation of Trypanosoma brucei procyclic form cells

ABSTRACT: T. brucei PF cells were treated with several chemical reagents and anti-trypanosomatid drugs. The effect of each chemical perturbation on the transcriptome of T. brucei was examined by transcript profiling of treated vs. control cells. The results indicated widespread changes, suggesting that the transcriptome of T. brucei is highly responsive to environmental factors that perturb its metabolic and biological pathways.

ORGANISM(S): Trypanosoma brucei

PROVIDER: GSE37593 | GEO | 2012/05/30

SECONDARY ACCESSION(S): PRJNA161897

REPOSITORIES: GEO

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