ChIP-seq of the HOXA9 and MEIS1 transcription factors in SEM cells.
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ABSTRACT: SEM cells were established from the peripheral blood of a 5-year-old girl in relapse with acute lymphoblastic leukaemia (ALL). SEM cells exhibit the t(4;11) chromosomal rearrangement, which leads to production of the MLL-AF4 fusion protein. Hematopoietic transcription factors including HOXA9 and MEIS1 are highly expressed in ALL.
ORGANISM(S): Homo sapiens
PROVIDER: GSE38339 | GEO | 2012/05/31
SECONDARY ACCESSION(S): PRJNA167740
REPOSITORIES: GEO
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