B-Raf activation cooperates with PTEN loss to drive c-Myc expression in advanced prostate cancer
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ABSTRACT: Anaysis of the response to different therapeutic agents at the transcriptional level. The design of the experiment allows to determine how the comnination target therapy (Rapamycin + PD0325901) treatment shifted the transcriptome towards a less aggressive or even a wild type phenotype. It also allows exploring the molecular changes involved in the transition from a non metastatic to a metastatic prostate cancer mouse model.
ORGANISM(S): Mus musculus
PROVIDER: GSE39190 | GEO | 2012/07/19
SECONDARY ACCESSION(S): PRJNA170931
REPOSITORIES: GEO
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