IL-17 and TNF synergistically induce growth-associated cytokines in melanocytes while suppressing melanogenesis
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ABSTRACT: In this study, we sought to determine how IL-17 and TNF influence normal human melanocytes, either alone, or with both cytokines together. We reveal a dichotomous effect of IL-17 and TNF, which not only elicit essential mitogenic cytokines but also suppress melanogenesis by down-regulating genes of melanogenesis pathway
ORGANISM(S): Homo sapiens
PROVIDER: GSE40413 | GEO | 2013/06/15
SECONDARY ACCESSION(S): PRJNA173896
REPOSITORIES: GEO
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