Transcriptomics

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IL-17 and TNF synergistically induce growth-associated cytokines in melanocytes while suppressing melanogenesis


ABSTRACT: In this study, we sought to determine how IL-17 and TNF influence normal human melanocytes, either alone, or with both cytokines together. We reveal a dichotomous effect of IL-17 and TNF, which not only elicit essential mitogenic cytokines but also suppress melanogenesis by down-regulating genes of melanogenesis pathway

ORGANISM(S): Homo sapiens

PROVIDER: GSE40413 | GEO | 2013/06/15

SECONDARY ACCESSION(S): PRJNA173896

REPOSITORIES: GEO

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