Gene expression signatures in a human bladder cancer cell line SW780 transfected with miR-137 precursor molecule
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ABSTRACT: To clarify the effect of miRNAs, we carried out a gene expression microarray analysis of SW780 cells transfected with a miR-137 precursor or a negative control. We found that 1,326 probe sets (1,016 unique genes) were downregulated (>2-fold) by ectopic miR-137 expression, including the previously reported miR-137 target genes CDK6, CDC42 and AURKA. Moreover, Gene Ontology analysis revealed that genes related to the cell cycle were significantly enriched among the affected genes.
ORGANISM(S): Homo sapiens
PROVIDER: GSE41760 | GEO | 2012/12/01
SECONDARY ACCESSION(S): PRJNA178119
REPOSITORIES: GEO
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