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Expression analysis of the first-generation offspring of irradiated male mice

ABSTRACT: Investigation of whole genome gene expression level changes in kidney, brain, liver and spleen of the offspring of CBA/Ca and BALB/c male mice exposed to 1 Gy of acute X-rays The pattern of gene expression of a number of circadian rhythm genes in the offspring of irradiated males is compromised

ORGANISM(S): Mus musculus

PROVIDER: GSE42621 | GEO | 2012/12/17

SECONDARY ACCESSION(S): PRJNA182367

REPOSITORIES: GEO

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Expression analysis of the first-generation offspring of irradiated male mice

Project description:Investigation of whole genome gene expression level changes in kidney, brain, liver and spleen of the offspring of CBA/Ca and BALB/c male mice exposed to 1 Gy of acute X-rays The pattern of gene expression of a number of circadian rhythm genes in the offspring of irradiated males is compromised A twenty-two 12x135K chip study using total RNA extracted from kidney, brain, liver and spleen of control CBA/Ca and BALB/c male mice and the first-generation offspring of male mice exposed to 1 Gy of acute X-rays. The expression of 42,575 genes was measured with two-fold technical redundancy.

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