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Global microRNA profiling of aTC1-6 and bTC1 before and after treatment with cytokines


ABSTRACT: The study sought to determine the global miRNA profiles of mouse pancreatic cell lines aTC1-6 and bTC1 at steady state and after treatment with a cocktail of pro-inflammatory cytokines (IL1b; IFNg and TNFa) for a time course of 24 and 48 hours. Inflammatory cocktail contains IL1b 50 IU/ml; IFNg 1000 IU/ml; TNFa 1000 IU/ml. MicroRNA expression profiles in both cell lines during the different experimental conditions were determined using TaqMan® Rodent miRNA A+B Cards Set v2.0 (TLDA, Life Technologies). MicroRNA profiles were measured in 3 independent biological replicates.

ORGANISM(S): Mus musculus

PROVIDER: GSE42970 | GEO | 2012/12/18

SECONDARY ACCESSION(S): PRJNA183965

REPOSITORIES: GEO

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