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Identification of unique cell type responses in pancreatic islets to stress

ABSTRACT: We single cell sequenced multiplexed primary human islets treated ex vivo with ER and inflammatory chemicals, indexed cell type specific stress responses, found genes to regulate in SC-islets to reduce apoptosis. We conducted multiomic ATAC+RNA sequencing on human islets treated with BFA, DMSO, IL1B+IFNG+TNFa, or PBS

ORGANISM(S): Homo sapiens

PROVIDER: GSE237448 | GEO | 2024/05/06

REPOSITORIES: GEO

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