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H3N2 canine influenza virus causes severe clinical signs in dogs with induction of genes related to inflammation and apoptosis

ABSTRACT: We demonstrated canine influenza virus (H3N2) pathogenicity to dogs using microarray analysis. Many genes related to innate immunity, such as toll-like receptors, immune cells of natural killer cells, macrophages, neutrophils, nitric oxide and reactive oxygen species, and interferon, were induced.

ORGANISM(S): Canis lupus familiaris

PROVIDER: GSE44545 | GEO | 2013/02/22

SECONDARY ACCESSION(S): PRJNA190044

REPOSITORIES: GEO

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