Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Transcriptional targets of Pou5f1 in Zebrafish (Danio Rerio)

ABSTRACT: This SuperSeries is composed of the SubSeries listed below.

ORGANISM(S): Danio rerio

PROVIDER: GSE45013 | GEO | 2013/12/31

SECONDARY ACCESSION(S): PRJNA192827

REPOSITORIES: GEO

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
		Other

Items per page:

1 - 1 of 1

Similar Datasets

Transcriptional targets of Pou5f1 in Zebrafish (Danio Rerio)

Project description:This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

2013-12-31 | E-GEOD-45013 | biostudies-arrayexpress

Pou5f1 transcription targets in zebrafish

Project description:This SuperSeries is composed of the SubSeries listed below.

2010-03-01 | GSE17667 | GEO

Natural Variation in Fish Transcriptomes: Comparative Analysis of the Fathead Minnow (Pimephales promelas) and Zebrafish (Danio rerio)

Project description:This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

2015-08-01 | E-GEOD-60202 | biostudies-arrayexpress

Methylmercury (MeHg) induced Transgenerational Inheritance of Brain Transcriptome in Zebrafish (Danio rerio)

Project description:This SuperSeries is composed of the SubSeries listed below.

2018-01-01 | GSE73797 | GEO

RNA profiling of the liver and gut tissues in zebrafish (Danio rerio)

Project description:This SuperSeries is composed of the SubSeries listed below.

2018-12-26 | GSE108437 | GEO

Transcriptional targets of Pou5f1 in Zebrafish (Danio Rerio)

Project description:Transcriptional targets of Pou5f1 in Zebrafish (Danio Rerio)

| PRJNA192827 | ENA

Natural Variation in Fish Transcriptomes: Comparative Analysis of the Fathead Minnow (Pimephales promelas) and Zebrafish (Danio rerio)

Project description:This SuperSeries is composed of the SubSeries listed below.

2015-08-01 | GSE60202 | GEO

Gene expression data from time course of fin regeneration in Danio rerio

Project description:This SuperSeries is composed of the SubSeries listed below.

2012-11-01 | GSE37165 | GEO

Identification of TWIST1 transcriptional targets in the cranial mesoderm

Project description:This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

2016-08-23 | E-GEOD-80663 | biostudies-arrayexpress

Functional characterization of zebrafish (Danio rerio) Bcl10.

Project description:The complexes formed by BCL10, MALT1 and specific members of the family of CARMA proteins (CBM complex), have recently focused much attention because they represent a central hub regulating activation of the transcription factor NF-κB following various cellular stimulations. In this manuscript, we report the functional characterization of a Danio rerio 241 amino acids polypeptide ortholog of the Caspase recruiting domain (CARD)-containing protein BCL10. Biochemical studies show that zebrafish Bcl10 (zBcl10) dimerizes and binds to components of the CBM complex. Fluorescence microscopy observations demonstrate that zBcl10 forms cytoplasmic filaments similar to that formed by human BCL10 (hBCL10). Functionally, in human cells zBcl10 is more effective in activating NF-κB compared to hBCL10, possibly due to the lack of carboxy-terminal inhibitory serine residues present in the human protein. Also, depletion experiments carried out through expression of short hairpin RNAs targeting hBCL10 indicate that zBcl10 can functionally replace the human protein. Finally, we show that the zebrafish cell line PAC2 is suitable to carry out reporter assays for monitoring the activation state of NF- kB transcription factor. In conclusion, this work shows that zebrafish may excellently serve as a model organism to study complex and intricate signal transduction pathways, such as those that control NF-κB activation.

| S-EPMC4388727 | biostudies-literature

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data