Transcriptomics

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Genome-wide identification of genes involved in tolerance to isopropanol in Saccharomyces cerevisiae


ABSTRACT: We performed massive screening of the genes in yeast that were involved in the tolerance to isopropanol using the non-essential genes deleted yeast collection, and identified sixty-five disruptants that grew slower than the wild type strain in the presence of isopropanol. The isopropanol sensitive mutants were tested to know their behaviour under other alcohol stresses. Besides, we conducted microarray analysis to reveal the transcriptional response to isopropanol stress in yeast. Our results certainly provide new insights into yeast response to C3 alcohol isopropanol.

ORGANISM(S): Saccharomyces cerevisiae

PROVIDER: GSE46384 | GEO | 2013/05/13

SECONDARY ACCESSION(S): PRJNA198898

REPOSITORIES: GEO

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