Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Gene expression profiles for murine submandibular gland stem cells

ABSTRACT: To compare the gene expression profile of submandibular gland stem cells to submandibular gland epithelia, we have employed whole genome microarray expression profiling as a discovery platform to identify genes with the differential expression in the stem cells and the non-stem cell epithelia.

ORGANISM(S): Mus musculus

PROVIDER: GSE46672 | GEO | 2014/07/01

SECONDARY ACCESSION(S): PRJNA201481

REPOSITORIES: GEO

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
		Other

Items per page:

1 - 1 of 1

Similar Datasets

Gene expression profiles for murine submandibular gland stem cells

Project description:To compare the gene expression profile of submandibular gland stem cells to submandibular gland epithelia, we have employed whole genome microarray expression profiling as a discovery platform to identify genes with the differential expression in the stem cells and the non-stem cell epithelia. Murine submandibular gland stem cells and non-stem cell epithelia are sorted through FACS

2014-07-01 | E-GEOD-46672 | biostudies-arrayexpress

Gene expression profile of murine submandibular gland epithelial cells

Project description:We examined effects of aging on gene expression profile of murine submandibular gland epithelial cells

2021-02-21 | GSE156682 | GEO

Functional characterization and genomic studies of a novel murine submandibular gland epithelial cell line.

Project description:Gene expression analysis of spontenously immortalized mouse submandibular salivary gland epithelial cells grown in culture at different passages and in different media conditions

2018-02-01 | GSE98250 | GEO

Genome-wide expression analysis of submandibular salivary gland tumours of Smgb-Tag mice

Project description:To reveal novel molecular factors behind the development of salivary gland cancer, we performed gene expression analyses from Smgb-Tag mouse salivary gland samples. The overall purpose was to apply these results for clinical use to find new approaches for both possible therapeutic targets and more accurate diagnostic tools in identification of salivary gland cancers. Smgb-Tag mouse strain, in which salivary neoplasms arise through a dysplastic phase in submandibular glands, was investigated using genome-wide microarray expression analysis, Ingenuity pathway analysis, RT-PCR, and immunohistochemistry. 3 normal, 3 dysplastic, and 3 adenocarcinomatous submandibular gland tumours of Smgb-Tag mice.

2014-09-30 | E-GEOD-61868 | biostudies-arrayexpress

Gene expression profile of murine submandibular gland epithelial cells

Project description:Gene expression profile of murine submandibular gland epithelial cells

| PRJNA658694 | ENA

Gene expression profiling in the submandibular gland, stomach, and duodenum of CAVI-deficient mice

Project description:In order to explore the functions of carbonic anhydrase VI (CAVI) more fully, we examined the transcriptomic responses to CAVI deficiency in the submandibular gland, stomach, and duodenum of Car6-/- mice by cDNA microarray. 94, 56, and 127 genes were up- or down-regulated in the above-mentioned tissues of Car6-/- mice, respectively. The functional clustering of differentially expressed genes revealed a number of altered biological processes. In the duodenum, the significantly affected biological pathways included immune system process and retinol metabolic process. Response to oxidative stress and brown fat cell differentiation changed remarkably in the submandibular gland. Notably, the submandibular gland, stomach, and duodenum shared one prominent transcriptional susceptibility pathway-catabolic process. Submandibular gland, stomach, and duodenum samples were collected from three wild-type and three Car6-/- female mice, respectively, at the age of two months. Total RNAs were purified and used for cDNA microarray.

2010-10-02 | E-GEOD-20423 | biostudies-arrayexpress

Adult parotid gland RNA-seq libraries, and embryonic submandibular gland RNA-seq libraries

Project description:Adult parotid gland RNA-seq libraries and embryonic submandibular gland RNA-seq libraries were created to examine the mRNA species present in these secretory glands, as part of a project to understand acinar glands in general.

2017-08-18 | GSE102788 | GEO

Human Submandibular Gland cells,secretory proteins,LC-MS/MS

Project description:In this work, Human Submandibular Gland (HSG) cells were treated for 24 hours with 0ng/mL, 2ng/mL, or 4ng/mL TGF-β1, respectively. Then, theirs cell supernatants were collected and prepared. We performed quantitave proteomic anaysis to investigate the changes in protein types and abundances among aforsied three groups. To screen out differentially regulated proteins, we compaired the expression levels of all quantified proteins among these three groups by using a label free quntification method.

2023-10-24 | PXD043185 | Pride

Single-cell transcriptome and TCR sequencing reveals immune cell heterogeneity in the submandibular gland of SS mice

Project description:In this study, we analyzed the submandibular gland and submandibular gland-draining lymph nodes of P40-/-CD25-/- (SS mice) and P40-/-CD25+/- (control mice) using single-cell transcriptome and TCR sequencing of leukocytes. A total of 24,115 cells were obtained for analysis, of which 9,897 cells were from the submandibular gland and 14,218 cells were from the draining lymph nodes. We found that tissue-resident CD8+T cells (CD8+Trm) in the submandibular gland of SS mice expanded massively and highly expressed PD-1. These CD8+Trm cells, which highly express PD-1, exhibit clonal expansion and cytotoxicity. In addition, shared TCR analysis found that potential CD8+Trm precursor cells in the draining lymph nodes exhibited a Gzmk+Pdcd1+ phenotype. In summary, we found that PD-1+CD8+Trm cells in the submandibular gland of SS mice are potentially pathogenic and their precursors also express PD-1.

2024-12-15 | GSE253042 | GEO

Expression data from human submandibular gland cell lines

Project description:Expression data from human submandibular gland cell lines

| PRJNA479984 | ENA