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Impaired Transcriptional Response of the Murine Heart To Cigarette Smoke in the Setting of High Fat Diet and Obesity

ABSTRACT: To identify biosignatures that describe these lifestyle susceptibility factors, we performed parallel exposures of regular weight (RW) C57BL/6 and diet-induced obese (DIO) C57BL/6 mice to cigarette smoke, either mainstream (MS) or sidestream (SS), mimicking both the smoker and environmental exposure through second-hand smoke, respectively. Transcriptional responses were measured by global microarray analysis of heart tissue.

ORGANISM(S): Mus musculus

PROVIDER: GSE47022 | GEO | 2013/05/17

SECONDARY ACCESSION(S): PRJNA203293

REPOSITORIES: GEO

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