Transcriptomics

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Gene expression in haematopoietic stem and progenitor cells from Gata1-EGFP reporter mouse bone marrow


ABSTRACT: Haematopoietic stem cells can differentiate into all blood cell types. In this process, cells become progressively restricted to a single cell type. The order in which differentiating cells loose lineage potential, and the prospective isolation of cells with a defined potential remains a long-standing question. We performed gene expression analysis of haematopoietic cells from Gata1-EGFP reporter mice, leading to a model for hematopoiesis where the initial lineage decision consists of a separation of erythroid/megakaryocyte/mast cell/eosinophil potential from lymphopoietic/monocyte/neutrophil potential

ORGANISM(S): Mus musculus

PROVIDER: GSE49241 | GEO | 2016/04/04

SECONDARY ACCESSION(S): PRJNA213377

REPOSITORIES: GEO

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