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Sensitivity to proteasome inhibition and in vivo growth properties of MCL cells

ABSTRACT: MCL cells resistant to bortezomib show distinct tumor growth in vivo when compared to their bortezomib-sensitive counterpart We used microarrays to detail the factors underlying the increased tumorigenicity of bortezomib-resistant cells in vivo

ORGANISM(S): Homo sapiens

PROVIDER: GSE51371 | GEO | 2013/10/18

SECONDARY ACCESSION(S): PRJNA222845

REPOSITORIES: GEO

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Sensitivity to proteasome inhibition and in vivo growth properties of MCL cells

Project description:MCL cells resistant to bortezomib show distinct tumor growth in vivo when compared to their bortezomib-sensitive counterpart We used microarrays to detail the factors underlying the increased tumorigenicity of bortezomib-resistant cells in vivo Global RNA expression in tumors harvested from SCID mice and derived from either bortezomib-sensitive or bortezomib-resistant MCL cell lines

2013-10-18 | E-GEOD-51371 | biostudies-arrayexpress

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