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Genome-wide transcriptome analysis of neuron-enriched DRG cultures exposed to Wnt3a

ABSTRACT: To test the potential of canonical Wnt signalling to modulate nociception via transcriptional regulation in dorsal root ganglion (DRG) neurons, we performed a genome-wide transcriptome analysis of neuron-enriched DRG cultures treated with Wnt3a or vehicle for 6 hours.

ORGANISM(S): Mus musculus

PROVIDER: GSE56880 | GEO | 2014/07/07

SECONDARY ACCESSION(S): PRJNA244879

REPOSITORIES: GEO

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Genome-wide transcriptome analysis of neuron-enriched DRG cultures exposed to Wnt3a

Project description:To test the potential of canonical Wnt signalling to modulate nociception via transcriptional regulation in dorsal root ganglion (DRG) neurons, we performed a genome-wide transcriptome analysis of neuron-enriched DRG cultures treated with Wnt3a or vehicle for 6 hours. Total RNA obtained from neuron-enriched mouse DRG culture subjected to Wnt3a treatment for 6 hours was compared to a matched control (vehicle-treated) DRG culture.

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