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Phenotypic analysis of conventional knockout mice lacking a protein responsible for ossification of the posterior longitudinal ligament

ABSTRACT: We found disease-specific proteins from serum proteomics of ossification of posterior longitudinal ligament, and made knockout mice. We discovered protein peculiar to a disease in serum of the ossification of posterior longitudinal ligament (OPLL), and, as a result of producing knockout mouse, we checked spinal ligament ossification and combination of diabetes and thought that it was a typical mouse and analyzed the sequence of the kidney organization.

ORGANISM(S): Mus musculus

PROVIDER: GSE57590 | GEO | 2018/05/01

REPOSITORIES: GEO

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