MDA-9/Syntenin regulates differentiation and angiogenesis programs in Head and Neck Squamous Cell Carcinoma
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ABSTRACT: We identified MDA-9/Syntenin (8q12) as a key component of HNSCC differentiation and angiogenesis. Robust reduction in the expression of cyclinD1, CDK4, CTNNB1, STAT3 and PI3K were evident in MDA- 9/Syntenein depleted cells, which was reversed following MDA-9/Syntenin overexpression in immortalized oral epithelial cells.
ORGANISM(S): Homo sapiens
PROVIDER: GSE57760 | GEO | 2015/11/23
SECONDARY ACCESSION(S): PRJNA248011
REPOSITORIES: GEO
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