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ChIP-seq profiling of loci bound by HIF1a in wild-type E12.5 hearts

ABSTRACT: Purpose: to identify genes directly bound by HIF1a in cardiomycoytes Methods: crosslinked chromatin isolated from E12.5 mouse hearts was precipitated using an anti-HIF1a antibody and processed for sequencing. A list of genes containing a HIF1a peak (Minimum score 3.5) was compared with RNA-seq results to identify genes that are bound by HIF1a and expressed in E12.5 hearts Results: this analysis identified 1016 genes expressed and bound by HIF1a in embryonic hearts

ORGANISM(S): Mus musculus

PROVIDER: GSE61247 | GEO | 2015/04/29

SECONDARY ACCESSION(S): PRJNA260618

REPOSITORIES: GEO

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RNA-seq profiling of transcriptomes of control and Hif1a mutant E12.5 hearts

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Project description:ChIP-seq profiling of loci bound by HIF1a in wild-type E12.5 hearts

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