Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Mus musculus

ABSTRACT: ChIP-seq profiling of loci bound by HIF1a in wild-type E12.5 hearts

PROVIDER: PRJNA260618 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR1571973.fastq.gz	Fastqsanger.gz
	SRR1571974.fastq.gz	Fastqsanger.gz
	SRR1571975.fastq.gz	Fastqsanger.gz

Items per page:

1 - 3 of 3

Similar Datasets

ChIP-seq profiling of loci bound by HIF1a in wild-type E12.5 hearts

Project description:Purpose: to identify genes directly bound by HIF1a in cardiomycoytes Methods: crosslinked chromatin isolated from E12.5 mouse hearts was precipitated using an anti-HIF1a antibody and processed for sequencing. A list of genes containing a HIF1a peak (Minimum score 3.5) was compared with RNA-seq results to identify genes that are bound by HIF1a and expressed in E12.5 hearts Results: this analysis identified 1016 genes expressed and bound by HIF1a in embryonic hearts

2015-04-29 | GSE61247 | GEO

Mus musculus

Project description:RNA-seq profiling of transcriptomes of control and Hif1a mutant E12.5 hearts

| PRJNA260617 | ENA

RNA-seq profiling of transcriptomes of control and Hif1a mutant E12.5 hearts

Project description:Purpose: to identify genes aberrantly expressed upon myocardial ablation of Hif1a Methods: a floxed Hif1a allele was deleted in mouse embryonic hearts using a NXK2.5Cre line. Total RNA was extracted from E12.5 hearts (n=3 for controls and mutants) usinz Trizol and processed for RNA-seq. Reads were mapped to Mm10 reference genome using TopHat2 and Bowtie2. Transcript expression values were determined after transcript normalization with AltAnalyze Results: this analysis revealed a total of 1451 genes significantely (|Fold| > 20% and P<0.05) modulated in Hif1a cKO hearts 6 total RNAseq runs with 3 experimental samples and 3 controls samples

2015-04-29 | E-GEOD-61209 | biostudies-arrayexpress

RNA-seq profiling of transcriptomes of control and Hif1a mutant E12.5 hearts

2015-04-29 | GSE61209 | GEO

Mouse embryo heart, e10.5 AVC: Control vs. Tbx3 hypomorphic mutant

Project description:Transcriptional profiling of the atrioventricular canal from e10.5 mouse hearts comparing wild-type control with Tbx3 GH/N hypomorphic mutant microdissected tissue. The goal was to identify direct and indirect targets of the transcription factor Tbx3, because Tbx3 is expressed in the AVC and hypomorphs develop embryonic AV conduction block at e12.5.

2011-04-01 | GSE24122 | GEO

Mouse embryo heart, e10.5 AVC: Control vs. Tbx3 hypomorphic mutant

2011-04-01 | E-GEOD-24122 | biostudies-arrayexpress

The Gene Expression Analysis in E12.5 Mouse Hearts with GATA4-FOG2 Interaction Loss

Project description:In order to identify the targets of GATA4-FOG2 action in mammalian heart development we performed Affymetrix microarray comparisons of gene expression in normal and mutant at embryonic (E) day E12.5 hearts. We compared RNA samples from both Fog2-null and Gata4ki/ki mutant E12.5 hearts to the wild-type control E12.5 hearts. We reasoned that as the phenotypes of the Fog2 knockout and Gata4ki/ki mutation (a V217G mutation that specifically cripples the interaction between GATA4 and FOG proteins) are similar, we should expect to identify a similar set of differentially expressed genes in both experiments. As an additional control, we expected to find the Fog2 gene expression absent in the mutant (null) Fog2 cardiac sample, but not Gata4ki/ki sample.

2010-02-18 | GSE14906 | GEO

Mus musculus

Project description:Gene expression profiling of E12.5 wildtype- and Sp3 null hearts

| PRJNA102663 | ENA

Mus musculus

Project description:Lmx1b ChIP-seq dataset in embryonic day 12.5 (e12.5) wild type mouse limb buds

| PRJNA327925 | ENA

The Gene Expression Analysis in E12.5 Mouse Hearts with GATA4-FOG2 Interaction Loss

2010-02-21 | E-GEOD-14906 | biostudies-arrayexpress