Transcriptomics

Dataset Information

0

Rare Allele of A Novel Histone H4 Acetyltransferase Enhances Grain Weight, Yield and Plant Biomass Presumably Through the Regulation of Transcription


ABSTRACT: Grain weight is an important crop yield component; however, its underlying regulatory mechanisms are largely unknown. Here, we identify a grain-weight quantitative trait locus (QTL) encoding a new-type GNAT-like protein that harbors intrinsic histone acetyltransferase activity (OsglHAT1). Our genetic and molecular evidences pinpointed the QTL-OsglHAT1’s allelic variations to a 1.2-kilobase region upstream of the gene body, which is consistent with its function as a positive regulator of the traits. Elevated OsglHAT1 expression enhances grain weight and yield by enlarging spikelet hulls via increasing cell number and accelerating grain filling, and increases global acetylation levels of histone H4. OsglHAT1 localizes to the nucleus, where it likely functions through the regulation of transcription. Despite its positive agronomical effects on grain weight, yield and plant biomass, the rare allele elevating OsglHAT1 expression has so far escaped human selection. Our findings reveal the first example, to our knowledge, of a QTL for a yield component trait being due to a chromatin modifier that has the potential to improve crop high-yield breeding.

ORGANISM(S): Oryza sativa

PROVIDER: GSE62554 | GEO | 2015/02/10

SECONDARY ACCESSION(S): PRJNA264408

REPOSITORIES: GEO

Dataset's files

Source:
Action DRS
Other
Items per page:
1 - 1 of 1

Similar Datasets

2015-02-10 | E-GEOD-62554 | biostudies-arrayexpress
2013-05-04 | GSE46616 | GEO
2013-05-04 | E-GEOD-46616 | biostudies-arrayexpress
2018-02-28 | E-MTAB-6383 | biostudies-arrayexpress
2024-06-30 | GSE256331 | GEO
2024-02-04 | GSE253343 | GEO
2024-03-20 | GSE232522 | GEO
2023-08-22 | GSE241093 | GEO
2015-01-31 | GSE65465 | GEO
2019-01-31 | GSE125891 | GEO