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Inflammatory cytokines activate unliganded estrogen receptor and alter the sensitivity of breast cancer cells to tamoxifen

ABSTRACT: Genome-wide analyses of the transcriptomes and transcription factor recruitment in estrogen receptor breast cancer cells in response to estradiol, IL1b, or TNFa treatments. Also, the role of inflammatory cytokines on affecting tamoxifen sensitivity is analyzed on a genome-wide scale.

ORGANISM(S): Homo sapiens

PROVIDER: GSE67295 | GEO | 2017/02/20

SECONDARY ACCESSION(S): PRJNA279424

REPOSITORIES: GEO

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