Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Transcriptional profiling of Candida albicans delta-doa1 mutant

ABSTRACT: The Candida albicans delta-doa1 mutant was investigated. This mutant shows lots of phenotypes. Doa1 protein has several WD 40 repeats. Keywords: mutant versus wildtype, comparative expression analysis

ORGANISM(S): Candida albicans

PROVIDER: GSE6905 | GEO | 2007/01/31

SECONDARY ACCESSION(S): PRJNA98155

REPOSITORIES: GEO

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
		Other

Items per page:

1 - 1 of 1

Similar Datasets

Cell wall and secretome of Candida albicans WT, hir1delta/delta strain, and HIR1 complemented mutant

Project description:Cell wall and secretome of Candida albicans WT, hir1delta/delta strain, and HIR1 complemented mutant using SWATH MS.

2022-02-15 | PXD018163 | Pride

Candida albicans

Project description:Transcriptional profiling of Candida albicans delta-doa1 mutant

| PRJNA98155 | ENA

Transcriptional profiling of Mms21 deleted (mms21Δ/Δ) mutant Candida albicans strains

Project description:Mms21 deleteion in Candida albicans resulted in invasveness and filamentatation in YPD media at 30 degrees Celsius. Wild type SN148 do not make any Filaments in YPD at 30 degrees Celsius. The aim was to look for transcription profiling mms21 dleleted mutant against wild type to find genes up and down regulated in the mutant especially thoseones critical for filamentation. Mms21 deleteion in Candida albicans resulted in invasveness and filamentatation in YPD media at 30 degrees Celsius. Wild type SN148 do not make any Filaments in YPD at 30 degrees Celsius. The aim was to look for transcription profiling mms21 dleleted mutant against wild type to find genes up and down regulated in the mutant especially thoseones critical for filamentation.

2018-07-03 | GSE116544 | GEO

Transcriptional profiling of Mms21 deleted (mms21Δ/Δ) mutant Candida albicans strains

Project description:Mms21 deletion in Candida albicans resulted in invasveness and filamentatation in YPD media at 30 degrees Celsius. Wild type SN148 do not make any Filaments in YPD at 30 degrees Celsius. The aim was to look for transcription profiling mms21 dleleted mutant against wild type to find genes up and down regulated in the mutant especially thoseones critical for filamentation

2018-10-23 | GSE121210 | GEO

Transcription profiling of wild type and dbr1-delta strains of Candida albicans grown under standard or various mixed conditions

Project description:Probes flanking all predicted Candida albicans ORFs are used to detect intron sequences that accumulate in a debranchase (DBR1) mutant. We synthesized cDNA from RNA from both wild-type and dbr1-delta mutant strains grown under standard (YEPD) or various mixed conditions, labeled the two populations differentially, and hybridized them together on our microarray.

2007-02-22 | E-MEXP-1003 | biostudies-arrayexpress

Candida albicans

Project description:Candida albicans rhb1 mutant transcriptome

| PRJNA407874 | ENA

Candida albicans SC5314

Project description:Candida albicans mutant transcriptome

| PRJNA350368 | ENA

Mitochondrial two-component signaling systems in Candida albicans

Project description:Two-component signal transduction pathways are one of the primary means by which microorganisms respond to environmental signals. These signaling cascades originated in prokaryotes and were inherited by eukaryotes via endosymbiotic lateral gene transfer from ancestral cyanobacteria. We report here that the nuclear genome of pathogenic fungus Candida albicans contains elements of a two-component signaling pathway that seem to be targeted to the mitochondria. In C. albicans two-component response regulator protein Srr1(Stress Response Regulator) contains a mitochondrial targeting sequence at the N-terminus, and fluorescence microscopy reveals mitochondrial localization of GFP-tagged Srr1p. Moreover, phylogenetic analysis indicates that C. albicans Srr1p is more closely related to histidine kinases and response regulators found in marine bacteria compared to other two-component proteins present in the fungi. These data suggest conservation of this protein during the evolutionary transition from endosymbiont to a subcellular organelle. We used microarray analysis to determine if the phenotypes observed with srr1Δ/Δ mutant could be correlated with gene transcriptional changes. Expression of mitochondrial genes was altered in the srr1Δ/Δ null mutant in comparison to the wild type. Furthermore, apoptosis significantly increased in the srr1Δ/Δ mutant strain compared to wild type, suggesting activation of mitochondria dependent apoptotic cell death pathway in the srr1Δ/Δ mutant. This study shows for the first time that a lower eukaryote like C. albicans possesses a two-component response regulator protein that has survived in mitochondria and regulates a subset of genes whose functions are associated with oxidative stress response and programmed cell death (apoptosis).

2013-07-02 | GSE45438 | GEO

Transcript profiling of Candida albicans tor1 kinase mutants

Project description:This study analyses the effects of truncation of the gene encoding Tor1 kinase in Candida albicans. The study involves a mutant tetO-TOR1-Del381 which has the N terminal regulator HEAT repeats deleted compared to a full length tetO-TOR1 strain and a heterozygous TOR1/tor1 control. Cell were grown in vitro in YEPD broth at 30˚C. In shut off experiments, doxycycline (30 µg.ml) was added to cultures to shut off the tetO promoter and inhibit Tor1 expression.

2021-08-17 | GSE182186 | GEO

Candida albicans: Control vs. sulfite-treated cells

Project description:Transcriptional profiling of Candida albicans cells comparing control untreated C. albicans cells with sulfite-treated C. albicans cells. Sulfite is a toxic molecule that C. albicans encounters in its human host. Both wild type and ∆zcf2 mutant cells were used. The goal was to determine the effects of sulfite on C. albicans gene expression, and to determine which of the genes areZcf2-depedent.

2016-12-03 | GSE90819 | GEO

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data