Transcriptomics

Dataset Information

0

BCL6 evolved in vertebrates as a stress tolerance gene and is broadly used by cancer cells to adapt to stress


ABSTRACT: We have found that BCL6 is a component of the conserved stress response program regulated by HSF1. BCL6 mediates cellular adaptation to stress by repressing genes through its BTB domain. These genes fail to be repressed after stress in a murine model with point mutations in the BCL6 BTB domain that disrupt its repressor activity.

ORGANISM(S): Mus musculus

PROVIDER: GSE69974 | GEO | 2019/11/20

REPOSITORIES: GEO

Dataset's files

Source:
Action DRS
Other
Items per page:
1 - 1 of 1

Similar Datasets

| S-EPMC6497559 | biostudies-literature
2013-03-03 | E-GEOD-43350 | biostudies-arrayexpress
2013-03-03 | GSE43350 | GEO
2020-11-20 | PXD016185 | Pride
2022-06-10 | GSE199739 | GEO
2021-11-19 | GSE161803 | GEO
2024-08-20 | GSE239778 | GEO
| S-EPMC7314397 | biostudies-literature
| PRJNA679550 | ENA
| S-EPMC3657141 | biostudies-literature