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Regulation of nucleosome positioning by a CHD Type III chromatin remodeller and its relationship to developmental gene expression in Dictyostelium [MNase-seq]

ABSTRACT: We utilized MNase-seq to profile nucleosome positions in wild type (Ax2) and ChdC null cells both in growing cells and a partially developed state (loose-mound) to study changes in nucleosome positioning and occupancy during development and the impact the deletion of ChdC an ATP-dependent chromatin remodeller has on nucleosome positioning and occupancy. As a control for MNase sequence bias we also digested naked DNA with MNase.

ORGANISM(S): Dictyostelium discoideum

PROVIDER: GSE70122 | GEO | 2017/02/26

SECONDARY ACCESSION(S): PRJNA287709

REPOSITORIES: GEO

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