Transcriptomics

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Profiling differentially expressed earthworm genes in response to TNT exposure.


ABSTRACT: To understand molecular mechanisms of the chronic, sublethal toxicity of 2,4,6-trinitrotoluene (TNT), a widely used ordnance compound of public concerns, we constructed a microarray consisting of 4,032 cDNA isolated from the earthworm Eisenia fetida using the suppressive subtractive hybridization technique. Worms were exposed to a gradient of TNT-spiked soil for 28 days. Based on the reproduction response to TNT, four treatments, i.e., control, 7, 35 and 139 ppm, were selected for gene expression studies. Keywords: Sublethal toxicity of TNT (dose-response) to earthworm (Eisenia fetida)

ORGANISM(S): Eisenia fetida

PROVIDER: GSE7024 | GEO | 2007/10/15

SECONDARY ACCESSION(S): PRJNA98375

REPOSITORIES: GEO

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