Transcriptomics

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DNA damage responses activate a multi-functional genetic program in murine bone marrow-derived macrophages


ABSTRACT: DNA damage response kinase ATM regulates the genetic program of lymphocytes with phsiologically induced DNA DSBs. In bone marrow-derived macrophages, related kinase DNAPKcs is also responsible for activating DNA damage responses after infection with Listeria monocytogenes. Here we show that both ATM and DNA-PKcs regulate the genetic program of Listeria monocytogenes-infected macrophages.

ORGANISM(S): Mus musculus

PROVIDER: GSE70467 | GEO | 2015/07/03

SECONDARY ACCESSION(S): PRJNA288753

REPOSITORIES: GEO

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