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The effect of progressive weight loss on metabolic function

ABSTRACT: The purpose of this study was to evaluate the effect of progressive weight loss (5, 10, 15% weight loss) on metabolic function such as multi-organ insulin sensitivity and beta-cell function in obese people. We conducted microarray analysis to determine the effect of progressive weight loss on adipose tissue gene expression profile.

ORGANISM(S): Homo sapiens

PROVIDER: GSE70529 | GEO | 2016/02/26

SECONDARY ACCESSION(S): PRJNA288954

REPOSITORIES: GEO

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The effect of progressive weight loss on metabolic function

Project description:The purpose of this study was to evaluate the effect of progressive weight loss (5, 10, 15% weight loss) on metabolic function such as multi-organ insulin sensitivity and beta-cell function in obese people. We conducted microarray analysis to determine the effect of progressive weight loss on adipose tissue gene expression profile. We examined subcuntaneous adipose tissue samples obtained from 9 obese subjects before (A) and after 5% (B), 10% (C) and 15% (D) weight loss (total 36 samples).

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