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Expression data from lung tissues of IPF patients and Normal Control

ABSTRACT: Idiopathic pulmonary fibrosis (IPF) is a progressive lethal interstitial lung disease of unkown etiology with limited effective therapies. The pathogenic mechanisms of IPF remain unkown. Emerging evidences indicate that abnormal behaviors of fibroblasts in IPF are associated with a variety of genetic alterations and aberrant reactivation of developmental signaling pathways. We compared gene expression profiles in fibrotic lung tissues from IPF patients and normal lung tissues from patients with primary spontaneous pneumothorax using cDNA microarray to examine the mechnisms involved in the pathogenesis of IPF.

ORGANISM(S): Homo sapiens

PROVIDER: GSE72073 | GEO | 2015/08/15

SECONDARY ACCESSION(S): PRJNA292870

REPOSITORIES: GEO

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