Transcriptomics

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Effect of Asr1 RING mutation on the transcriptome of S. cerevisisae.


ABSTRACT: This analysis identified 27 genes that are induced, and 29 that are repressed, by a factor of two or more in Asr1RING mutant cells. Genes in each category did not cluster according to gene ontology or chromosome, but we did notice that 33% of genes in the induced set lie within 50 kb of a telomere. In contrast, for repressed genes, only 7% were similarly telomere-proximal. The induction of subtelomeric gene expression in Asr1RING mutant cells suggests that the Ub-ligase activity of Asr1 may be required for authentic patterns of subtelomeric gene silencing.

ORGANISM(S): Saccharomyces cerevisiae

PROVIDER: GSE72740 | GEO | 2016/01/31

SECONDARY ACCESSION(S): PRJNA295088

REPOSITORIES: GEO

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