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Neutrophils oppose uterine epithelial carcinogenesis via debridement of hypoxic tumor cells

ABSTRACT: Our study demonstrates that neutrophils infiltrate early-stage PTEN-deficient uterine tumors and oppose tumor growth and malignant progression by inducing detachment and ultimately promoting cell death of tumor cells. This RNA-seq study examined the expression profiles of these uterine epithelial tumor cells in the presence versus absence of neutrophil infiltration.

ORGANISM(S): Mus musculus

PROVIDER: GSE73541 | GEO | 2015/09/29

SECONDARY ACCESSION(S): PRJNA297245

REPOSITORIES: GEO

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