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ATFS-1 regulates a broad protective transcriptional program

ABSTRACT: We previously identified a number of genes which were differentially expressed during mitochondrial stress in an ATFS-1-dependent manner using an atfs-1 loss-of-function mutant allele . To complement the findings from our previous microarray, we compared the transcript profiles from wild-type and atfs-1(et18) gain-of-function worms (which have constitutively active ATFS-1) in the absence of mitochondrial stress. We used microarrays to identify genes regulated by ATFS-1 using a gain-of-function allele of atfs-1.

ORGANISM(S): Caenorhabditis elegans

PROVIDER: GSE73669 | GEO | 2016/03/21

SECONDARY ACCESSION(S): PRJNA297595

REPOSITORIES: GEO

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ATFS-1 mediates a protective transcription program during mitochondrial stress

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