Genomics

Dataset Information

0

Next generation sequencing identifies circulating microRNAs in cardiac arrest patients


ABSTRACT: The goal of this study is to identify circulating microRNAs with prognostic value in a large cohort of comatose survivors of out-of-hospital cardiac arrest. We performed RNA-Seq for short RNAs in plasma, collected 48 hours after return of spontaneous circulation, of 50 cardiac arrest patients including 25 good neurological outcome at 6 months (cerebral performance category 1) and 25 poor neurological outcome including death at 6 months (cerebral performance category score 5). The sequencing generated on average 18.5 million reads per sample. After mapping the reads and counting to relevant entries in miRBase 20, we found 236 microRNAs detected in all 50 samples with TPM above or equals to 1. 11 microRNAs were differentially expressed between 2 groups with False Discovery Rate (FDR) < 5%.

ORGANISM(S): Homo sapiens

PROVIDER: GSE74198 | GEO | 2020/07/15

REPOSITORIES: GEO

Dataset's files

Source:
Action DRS
Other
Items per page:
1 - 1 of 1

Similar Datasets

2013-06-01 | E-GEOD-29540 | biostudies-arrayexpress
2017-01-01 | GSE92696 | GEO
2019-03-21 | E-MTAB-7699 | biostudies-arrayexpress
| PRJNA151255 | ENA
2013-01-11 | E-GEOD-34643 | biostudies-arrayexpress
2022-11-02 | GSE197764 | GEO
2013-06-01 | GSE29540 | GEO
2024-02-27 | PXD041236 | Pride
2023-10-24 | PXD040592 | Pride
2022-07-25 | GSE209531 | GEO