Transcriptomics

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Single cell transcriptome analysis of mouse carotid body glomus cells


ABSTRACT: The carotid body (CB) is a major arterial chemoreceptor containing glomus cells whose activities are regulated by changes in arterial blood contents including oxygen. We employed the single cell RNA­Seq method by performing next-generation sequencing on single glomus cell­derived cDNAs to eliminate contamination of genes derived from other cell types present in the CB. This study has generated a CB expression profile containing novel glomus cell specific genes. The wealth of information provided through this study offers a valuable foundation for identifying molecules functioning in the CB.

ORGANISM(S): Mus musculus Mus musculus x Mus spretus

PROVIDER: GSE76579 | GEO | 2016/03/15

SECONDARY ACCESSION(S): PRJNA308083

REPOSITORIES: GEO

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