Identification of loci and signaling pathways associated with ITP using pooling genome-wide association study in Han Chinese
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ABSTRACT: Immune thrombocytopenia (ITP) is an autoimmnue bleeding disorder characterized by low platelet count. To identify susceptibility loci for disease progression of ITP, we performed this genome-wide association study using DNA pools of 200 ITP cases and 200 controsl in Han Chinese. Performing GWAS on pools of DNA samples is an effective strategy to reduce the costs of studies and pooling DNA has been shown to be an efficient method to select candidate susceptibility loci for follow-up by individual genotyping.
ORGANISM(S): Homo sapiens
PROVIDER: GSE76744 | GEO | 2016/01/12
SECONDARY ACCESSION(S): PRJNA308485
REPOSITORIES: GEO
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