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Robustness of gene expression signatures in leukemia: comparison of three distinct total RNA preparation procedures.

ABSTRACT: Microarray gene expression (MAGE) signatures allow insights into the transcriptional processes of leukemias and may evolve as a molecular diagnostic test. Introduction of MAGE into clinical practice of leukemia diagnosis will require comprehensive assessment of variation due to the methodologies. For the first time, we present a study focused on analyzing the impact of different RNA preparation procedures on gene expression data for different subtypes of pediatric acute leukemias. Keywords: comparison of various total RNA preparation procedures

ORGANISM(S): Homo sapiens

PROVIDER: GSE7757 | GEO | 2007/05/31

SECONDARY ACCESSION(S): PRJNA99883

REPOSITORIES: GEO

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