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Gene expression profiles of various CSB mutant cell lines

ABSTRACT: A new ubiquitination site of CSB was identified and proved to play roles in oxidative stress repair. This study characterizes the gene expression signatures affected by CSB-K991R as compared to wild type and UBD mutant. Using Nimblegen microarray we identified differentially expressed genes in human fibroblasts derived from CS patients as compared to CSB reconstituted cell lines (wild type), also we found the similar gene expression patterns between K991R and UBD mutant derivatives.

ORGANISM(S): Homo sapiens

PROVIDER: GSE77680 | GEO | 2016/05/05

SECONDARY ACCESSION(S): PRJNA311201

REPOSITORIES: GEO

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