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A microfluidics-based in vitro model of the gastrointestinal human-microbe interface

ABSTRACT: We have developed a microfluidics-based in vitro model of the human gut allowing co-culture of human and microbial cells and subsequent multi-omic assessment of the effect of the co-culture on the host transcriptome. We compare the transcriptional changes induced in the human epithelial cell line, Caco-2 after co-culture with Lactobacillus rhamnosus GG or a consortium of Lactobacillus rhamnosus GG and Bacteroides caccae.

ORGANISM(S): synthetic construct Homo sapiens

PROVIDER: GSE79383 | GEO | 2016/05/05

SECONDARY ACCESSION(S): PRJNA315665

REPOSITORIES: GEO

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A microfluidics-based in vitro model of the gastrointestinal human-microbe interface

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