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DNA methylation profile of PBMC following decitabine therapy

ABSTRACT: The epigenetic regulation, for example, DNA methylation, controls the development and differentiation of both tumor cells and immunocytes. Treatment with DNA demethylating agent (such as decitabine) has shown a dramatic clinical benefit in hematological malignancies and solid tumors. However, the influence of epigenetic therapy on host immune system remains unclear.

ORGANISM(S): Homo sapiens

PROVIDER: GSE80377 | GEO | 2016/12/01

SECONDARY ACCESSION(S): PRJNA318770

REPOSITORIES: GEO

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