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Identification of Kdm4a, b and c target genes in MLL-AF9 transformed mouse GMPs (L-GMP) [gene expression]

ABSTRACT: In this study we identify genes, that are deregulated in Kdm4a, b and c triple knockout L-GMP cells compared WT L-GMP cells.

ORGANISM(S): Mus musculus

PROVIDER: GSE81298 | GEO | 2016/06/02

SECONDARY ACCESSION(S): PRJNA321214

REPOSITORIES: GEO

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Identification of Kdm4a, b and c target genes in MLL-AF9 transformed mouse GMPs (L-GMP) [gene expression]

Project description:In this study we identify genes, that are deregulated in Kdm4a, b and c triple knockout L-GMP cells compared WT L-GMP cells. Four MLL-AF9 transformed L-GMP cell lines conditional knockout for Kdm4a, b and c, were derived from leukemic mice. The cells were treated with 4-hydroxytamoxifen and total RNA was prepared from 0h, 48h and 96h time points.

2016-06-02 | E-GEOD-81298 | biostudies-arrayexpress

Identification of Kdm4a and c target genes in MLL-AF9 transformed mouse GMPs (L-GMP) [ChIP-seq]

Project description:In this study we identify genes, that are bound by Kdm4a and Kdm4c in L-GMP cells. MLL-AF9 transformed L-GMP cell lines conditional knockout for Kdm4a, b and c, were derived from leukemic mice. The cells were treated with 4-hydroxytamoxifen and chromatin was prepared from untreated cells (Ctrl) and cells treated for 96hr.

2016-06-02 | E-GEOD-81299 | biostudies-arrayexpress

Identification of Kdm4a and c target genes in MLL-AF9 transformed mouse GMPs (L-GMP) [ChIP-seq]

Project description:In this study we identify genes, that are bound by Kdm4a and Kdm4c in L-GMP cells.

2016-06-02 | GSE81299 | GEO

Identification of Kdm4a, b and c target genes in MLL-AF9 transformed mouse GMPs (L-GMP)

Project description:Identification of Kdm4a, b and c target genes in MLL-AF9 transformed mouse GMPs (L-GMP)

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Identification of Kdm4a, b and c target genes in MLL-AF9 transformed mouse GMPs (L-GMP)

Project description:This SuperSeries is composed of the SubSeries listed below.

2016-06-02 | GSE81300 | GEO

Identification of Kdm4a, b and c target genes in MLL-AF9 transformed mouse GMPs (L-GMP)

Project description:This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

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Histone demethylase KDM4A-mediated promotion of PAF1/NFATC2 expression is required for oncogenesis in MLL-AF9 acute myeloid leukemia [ChIP-seq]

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