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The different gene expression profile of knockdown LRP5/6 or knockdown β-catenin in hepG2 cell line through RNA-Seq

ABSTRACT: LRP5/6 receptor is an important receptor for the activation of β-catenin. Therefore, the downregulation of LRP5/6 can lead to the degradation of β-catenin. We sequenced mRNA from hepG2 cell after knocking down LRP5/6 or β-catenin separately by siRNA for 48hour. The different expression profile of mRNA was studied in two groups.

ORGANISM(S): Homo sapiens

PROVIDER: GSE83254 | GEO | 2017/06/13

SECONDARY ACCESSION(S): PRJNA325443

REPOSITORIES: GEO

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Tetraspanin TSPAN12 regulates tumor growth and metastasis and inhibits β-catenin degradation

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