Project description:The presence of HBeAg has been linked to an increased risk of HBV-realted HCC. However, the biological role of HBeAg in modulating host gene expression is poorly understood. Therefore, we performed a cDNA microarray in response to presence of HBeAg in Huh-7 cells. We used human primeview gene expression microarray chips to assess the host cellular mRNA expression profile in response to HBeAg in Huh7 cells
Project description:The HBeAg is a well-documented risk factor for HCC in epidemiological studies. The biological role of HBeAg in HBV-related HCC remains poorly understood. The HBeAg-mediated differential expression of host miRNAs We used miRNA microarray chips to assess the host cellular miRNA expression profile in response to HBeAg expression in Huh7 cells