Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Effect of Lipiodol on Dendritic Cell

ABSTRACT: Hysterosalpingography with Lipiodol is known to enhance fertility. Frequency of mature dendritic cell of pertitoneal cavity is higher in the patients after hysterosalpingography with Lipiodol than control. In order to elucidate the mechanism of fertility enhancing effect of Lipiodl, we used microarray to clarify the effect of Lipiodol on dendritic cells.

ORGANISM(S): Homo sapiens

PROVIDER: GSE95485 | GEO | 2018/02/28

REPOSITORIES: GEO

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
		Other

Items per page:

1 - 1 of 1

Similar Datasets

Gene expression by Retinoic Acid in mouse Dendritic Cells

Project description:The purpose of this study was to determine and clarify the retinoic effect on the gene expression profile for mouse dendritic cells.

2013-02-26 | GSE34324 | GEO

Gene expression by Retinoic Acid in mouse Dendritic Cells

Project description:The purpose of this study was to determine and clarify the retinoic effect on the gene expression profile for mouse dendritic cells. Dendritic cells were prepared from marrow cells by culturing them for 10 days with GM-CSF (20 ng/ml). These cells were cultured with the following reagents from the beginning of the culture: Two groups of dendritic cell conditions (Control, all-trans-retinoic acid (10 nmol) and Ro41-5253 (100 nmol)) with and without LPS(1 ug/ml). The above conditions were done in BALB/c and BL6 mouse strains and compared for reproducible gene expression.

2013-02-26 | E-GEOD-34324 | biostudies-arrayexpress

Intestinal alcohol abuse sorted dendritic cells proteomics

Project description:Consumption of ethanol has detrimental effects on gastric organs such as the intestine. To demonstrate the deleterious effect of alcohol, we sacrificed isobaric feeding or ethanol feeding mice and sorted the dendritic cells from their intestine organ. The dendritic cells were analyzed by a small-scale global proteomics approach. We achieved to obtain the biological signatures in the alcohol abuse mice group using bioinformatics analysis.

2024-06-16 | PXD033700 | Pride

Zeb2 regulates commitment to plasmacytoid dendritic cell and monocyte fate (part 2)

Project description:Recent studies have identified Zeb2 as a transcription factor important for the final maturation of natural killer cells and effector CD8+ T cells. We show that Zeb2 is required for the development of two myeloid cell types, the monocyte and the plasmacytoid dendritic cell, and clarify that this factor is not required for the development of classical dendritic cells.

2016-11-01 | GSE87883 | GEO

Zeb2 regulates commitment to plasmacytoid dendritic cell and monocyte fate (part 1)

2016-11-01 | GSE87882 | GEO

Effect of nociceptors on dendritic cells

Project description:Effect of nociceptors on dendritic cells

| PRJNA899115 | ENA

Comparative gene expression profile of 1,25-dihydroxyvitamin D3-treated human monocyte-derived dendritic cells

Project description:We have carried out global gene expression analysis to clarify the interrelationship between 1,25-dihydroxyvitamin D3 and differentiation-driven gene expression patterns in developing human monocyte-derived dendritic cells. Monocytes were treated with 10 nM 1,25-dihydroxyvitamin D3 or vehicle 14 hours after plating for 12 hours or 5 days. Monocytes, differentiating dendritic cells (+/-1,25-dihydroxyvitamin D3 for 12 hours) and immature dendritic cells (+/-1,25-dihydroxyvitamin D3 for 5 days) were harvested. This design allows one to identify genes regulated by differentiation and/or 1,25-dihydroxyvitamin D3 in human monocyte-derived dendritic cells.

2009-02-15 | GSE13762 | GEO

Inflammatory Activation Drives Re-Sculpting and Shear-Thinning of the Dendritic Cell Nucleus

Project description:To mount an adaptive immune response, dendritic cells must migrate to lymph nodes to present antigens to T cells. Critical to 3D migration is the nucleus, which is the size-limiting barrier for migration through the extracellular matrix. Here, we show that inflammatory activation of dendritic cells leads to the nucleus becoming spherically deformed and enables dendritic cells to overcome the typical 2- to 3-μm diameter limit for 3D migration through gaps in the extracellular matrix. We show that the nuclear shape change is partially attained through reduced cell adhesion, whereas improved 3D migration is achieved through reprogramming of the actin cytoskeleton. Specifically, our data point to a model whereby the phosphorylation of cofilin-1 at serine 41 drives the assembly of a cofilin-actomyosin ring proximal to the nucleus and enhances migration through 3D collagen gels. In summary, these data describe signaling events through which dendritic cells deform their nucleus and enhance their migratory capacity.

2024-03-14 | PXD031056 | Pride

Pembrolizumab and Autologous Dendritic Cells for the Treatment of Refractory Colorectal Cancer (CRC)

Project description:The phase II trial tests whether pembrolizumab and dendritic cell-based treatment works to shrink tumors in patients with colorectal cancer that does not respond to treatment (refractory). Pembrolizumab, also referred to as an immune checkpoint inhibitor drug, works by targeting molecules that act as a check and balance system for immune responses. Immune checkpoint inhibitor drugs are designed to either "unleash" or "enhance" the cancer immune responses that already exist by either (1) blocking inhibitory molecules or by (2) activating stimulatory molecules. Dendritic cell-based treatment works by boosting the immune system (a system in our bodies that protects us against infection) to recognize and destroy the cancer cells. This investigational treatment targets cancer cells and is made from the patient’s own blood cells. Giving pembrolizumab and dendritic cell-based treatment may help shrink tumors in patients with colorectal cancer.

| 2746535 | ecrin-mdr-crc

Effect of Sec61 inhibitor mycolactone on the proteome of the MutuDC dendritic cell line

Project description:Here we used a newly identified Sec61 blocker, mycolactone, to analyze Sec61 contribution to antigen cross presentation, ERAD and transport of internalized antigens into the cytosol in dendritic cells. Shotgun proteomics were used to asses the broad-ranging effects of Sec61 blockade on dendritic cells and its effect on critical proteins required for antigen presentation and ERAD.

2017-07-11 | PXD006103 | Pride

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data