Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

MLE12 cell transcriptome analysis 12, 24, 48h after Notch 1-ICD overexpression with NICD1-pIRES-dsRed2 vector

ABSTRACT: To study the effect of Notch 1 overexpression on cell funtion and to elucidate involved signalling pathways MLE12 cells tranfected with NICD1-pIRES-dsRed2 vector were analyzed for their transcript profiles 12, 24, and 48h after transfection and related to an empty vector (EV) transfected control cells

ORGANISM(S): Mus musculus

PROVIDER: GSE95856 | GEO | 2018/03/01

REPOSITORIES: GEO

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
		Other

Items per page:

1 - 1 of 1

Similar Datasets

Osteopontin vs empty vector

Project description:Osteopontin tranfected vs empty vector breast cell line Keywords: parallel sample

2004-01-07 | GSE939 | GEO

Mus musculus

Project description:MLE12 cell transcriptome analysis 12, 24, 48h after Notch 1-ICD overexpression with NICD1-pIRES-dsRed2 vector

| PRJNA378607 | ENA

Transcription profiling of human breast cancer cell line transfected with osteopontin vs empty vector

Project description:Osteopontin tranfected vs empty vector breast cell line

2008-06-16 | E-GEOD-939 | biostudies-arrayexpress

Transcription profiling of human HEK cells and hamster A23 cells transfected with Pcdh7 (a gene identified as a regulator of many genes) or empty vector to validate results of prediction of upregulated genes

Project description:We have mapped regulatory loci for nearly all protein coding genes in the mammalian genome using microarray measurements from a panel of mouse/hamster radiation hybrids. Proof of principle transfection experiment. Pcdh7 (a gene identified as being a regulator of many genes) is transfected into A23 and HEK cells and compared to A23 and HEK cells transfected with an empty vector. Upregulated genes predicted by our approach are compared with the transfection experiments Experiment Overall Design: There are 4 microarrays. The first two are biological replicates of A23 (transfected with Pcdh7, labeled with cy5) / A23 (tranfected with empty vector, labeled with cy3). The second two are biological replicates of HEK (transfected with Pcdh7, labeled with cy5) / HEK (tranfected with empty vector, labeled with cy3).

2008-04-03 | E-GEOD-9066 | biostudies-arrayexpress

RNA-seq of Anopheles gambiae 24 and 48h post Trypanosoma infection

Project description:RNA deep seq responses of Anopheles gambiae 24 and 48h post Trypanosoma infection

2020-03-04 | E-MTAB-7469 | biostudies-arrayexpress

Vector

Project description:Vector Targeted Locus (Loci)

| PRJNA315083 | ENA

48h Immobilization in human

Project description:Our results suggest that 48h of immobilization increases expression of mRNA for components of the UPP and MT function while decreasing mRNA and protein for components involved in ECM integrity. We hypothesized that 48h of immobilization would increase gene expression and respective protein products for components of the ubiquitin proteasome pathway (UPP). Keywords: stimulus or stress design

2006-06-20 | GSE5110 | GEO

RNA-seq for siRNA 48h

Project description:RNA-seq for siRNA 48h

| PRJNA742365 | ENA

Comprehensive gene expression analysis in liver tissue following forced activation of Notch1 and Notch2 signaling.

Project description:We compared the effects of Notch1 and Notch2 signaling induced by AAV8-mediated forced expression of Notch1 intracellular domain (NICD1) and Notch2 intracellular domain (NICD2), respectively, in the liver. Eight-week-old wild-type male mice were injected intraperitoneally with an NICD1- and/or NICD2-overexpressing AAV8 vector. Efficient AAV8-mediated gene transfer was confirmed by co-expressed green fluorescent protein (GFP) fluorescence in hepatocytes. A comprehensive gene expression analysis using DNA microarray indicated that the expression levels of 1704 and 1325 genes were altered by overexpressing NICD1 and NICD2, respectively, compared with the control group expressing only GFP.

2021-11-28 | GSE178886 | GEO

RNA-seq of Anopheles gambiae 24 and 48h post Trypanosoma infection

Project description:RNA-seq of Anopheles gambiae 24 and 48h post Trypanosoma infection

| PRJEB30081 | ENA