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Impact of DNA demethylation agents (5-azacitidine or vitamin C) on DNA copy number in gliobalstoma HSR-GBM1 cells

ABSTRACT: Glioblastoma HSR-GBM1 cells have low mitochondrial DNA copy numbers which is associated with the abnormal DNA methylation patterns. By inducing DNA demthylation using 5azacitidine and vitamin C, HSR-GBM1 cells modulate their mitochondrial copy number and capability of diffrentiation.

ORGANISM(S): Homo sapiens

PROVIDER: GSE98377 | GEO | 2018/12/26

REPOSITORIES: GEO

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